Pathology: Decrease in conduction ofimpulse from atria to ventricles through AV node.
Manifested as a prolonged PR interval(>02s) on ECG
Aetiology: Drug therapy e.g. beta blockade, fibrosis ofconductive tissue, Lyme disease, acute rheumatic fever, aortic valve disease, sarcoidosis,myocarditis, MI, idiopathic
Signs: None
Symptoms: Usuallynone
Investigations: ECG: see fig 1.8
Treatment: Nonerequired
Complications: None
Prognosis: Good
Figure 1.8 1st degree heart block with PRinterval of 292ms
Pathology: Intermittentfailure of atrial impulses to be conducted through AV node and His bundle, subdividedinto Mobitz type 1 (Wenckebach) or Mobitz type 2
Mobitz type 1: delayin AV conduction progressively increases until an impulse
is not conducted, on the ECG the PR interval getslonger and longer until there is a dropped beat
Mobitz type 2: intermittentfailure of conduction of the atrial impulse to the
ventricles usually in a 2:1 ratio, the PR intervaldoes not lengthen
Aetiology: Mobitz type 1 can be due toincreased vagal tone and often occurs during sleep
Mobitz type 2is pathological and has a similar aetiology to 1st degree AVblock
Symptoms: Can be asymptomatic, SOB,chest pain, pre-syncope/syncope
Signs: Bradycardia,hypotension
Investigations: ECG:To assess rhythm; may require a Holter monitor
Echo:if LV function impaired the patient may benefit from CRT
Treatment: Stop offending medications
A temporary pacing wire may be required
Mobitz type 2 always requires a permanent pacemaker
Complications: Death, injuries from syncope
Prognosis: Both Mobitz type 1 and 2 canprogress to complete heart block
Prognosisis good following PPM implantation
Figure 1.9 2ndDegree Heart Block – Mobitz Type I (Top) Mobitz Type II (Bottom)
Pathology: Complete AV dissociation, impulsesfrom atria cannot be conducted to ventricles
Aetiology: Drugtherapy e.g. beta blockade, fibrosis of conductive tissue, Lyme disease, acuterheumatic fever, aortic valve disease, sarcoidosis, myocarditis, MI, idiopathic
Signs: Bradycardia,hypotension
Symptoms: Canbe asymptomatic, SOB, chest pain, pre-syncope/syncope
Investigations: ECG:No association between p-waves and ventricular conduction
Echo: To assess for any structuralabnormalities
Treatment: Stopoffending drugs
A temporary pacing wire may be required
Long-term PPM
Complications: Death, injuries from syncope
Prognosis: Untreated at high risk ofsudden cardiac death, once treated prognosis is good
Figure 1.10 Complete Heart Block