Haemolytic Uraemic Syndrome

Haemolytic Uraemic Syndrome

Pathology:                    Endothelialdamage triggers deposition of fibrin, which damages passing red blood cellscausing:

Triad of:AKI, thrombocytopenia and haemolysis with red cell fragmentation


Aetiology:                     Post-infection:classically E. Coli 0157:H7 or Shigella dysenteriae


Symptoms:                   Haematuria, bloody diarrhoea, vomiting,abdominal pain, oliguria, fatigue


Signs:                              Pallor, petechiae, hypertension


Investigations:          Bloods: FBC, U&E, Clotting, Bloodfilm

                                          Urine: Haematuria

                                          Stool Culture: Assess for bacterialinfection


Treatment:                  Supportive: IVI fluids, dialysis


Complications:          CRF,hypertension


Prognosis:                   5% mortality

Join Shiken For FREE

Gumbo Study Buddy

Explore More Subject Explanations

Try Shiken Premium
for Free

14-day free trial. Cancel anytime.
Get Started
The first 14 days are on us
96% of learners report x2 faster learning
Free hands-on onboarding & support
Cancel Anytime