The haemostatic system within the intravascular system is activated, resulting in the widespread deposition of fibrin, activation of platelets and consumption of various coagulation factors.
Patients may experience excessive bleeding.
Bloods: Clotting screen shows prolonged prothrombin time, activated partial thromboplastin time, thrombin time and a decreased fibrinogen level, as well as a raised D-Dimer level.
Red blood cell fragmentation may be observed.
Mortality rate is greater than 80% in severe cases.