Cor Pulmonale

Cor Pulmonale

Pathology:                    Rightheart failure due to chronic pulmonary hypertension


Aetiology:                     Anycause of pulmonary hypertension.

Pulmonary vascular disease: acute pulmonary embolism, primarypulmonary hypertension, chronic pulmonary embolism, parasitic infection

Lung disease: COPD, asthma, pulmonary fibrosis,bronchiectasis

Chronic hypoventilation: motor neurone disease, myastheniagravis, kyphosis, scoliosis, OSA


Symptoms:                  Dyspnoea,fatigue, anorexia, weight loss


Signs:                              Peripheraloedema, raised JVP, right ventricular heave, cyanosis, tricuspid regurgitation,hepatomegaly, cyanosis


Investigations:         ECG: Right ventricular hypertrophy andright axis deviation, P pulmonale.

Chest X-Ray: Right atrial enlargement, cardiomegaly

FBC: Polycythaemia.

ECHO: Right ventricular dysfunction, tricuspidregurgitation and estimation of right

sided pressures


Treatment:                  Treatthe underlying cause, oxygen if hypoxic, diuretics, heart-lung transplantation


Complications:          Arrhythmia,liver failure


Prognosis:                    Poor,50% 5 year mortality

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